The ultraviolet B inflammation model: Postinflammatory hyperpigmentation and validation of a reduced UVB exposure paradigm for inducing hyperalgesia in healthy subjects

BACKGROUND: Pain models are commonly used in drug development to demonstrate analgesic activity in healthy subjects and should therefore not cause long‐term adverse effects. The ultraviolet B (UVB) model is a model for inflammatory pain in which three times the minimal erythema dose (3MED) is typica...

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Detalhes bibliográficos
Publicado no:Eur J Pain
Main Authors: Siebenga, Pieter S., van Amerongen, Guido, Klaassen, Erica S., de Kam, Marieke L., Rissmann, Robert, Groeneveld, Geert Jan
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6590423/
https://ncbi.nlm.nih.gov/pubmed/30597682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ejp.1353
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