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Understanding the importance of low‐molecular weight (ethylene oxide‐ and propylene oxide‐induced) DNA adducts and mutations in risk assessment: Insights from 15 years of research and collaborative discussions

The interpretation and significance of DNA adduct data, their causal relationship to mutations, and their role in risk assessment have been debated for many years. An extended effort to identify key questions and collect relevant data to address them was focused on the ubiquitous low MW N7‐alkyl/hyd...

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Detalhes bibliográficos
Publicado no:Environ Mol Mutagen
Main Authors: Pottenger, L. H., Boysen, G., Brown, K., Cadet, J., Fuchs, R. P., Johnson, G. E., Swenberg, J. A.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6590209/
https://ncbi.nlm.nih.gov/pubmed/30536466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.22248
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