Nanoscale Molecular Reorganization of the Inhibitory Postsynaptic Density Is a Determinant of GABAergic Synaptic Potentiation

Gephyrin is a key scaffold protein mediating the anchoring of GABAA receptors at inhibitory synapses. Here, we exploited superresolution techniques combined with proximity-based clustering analysis and model simulations to investigate the single-molecule gephyrin reorganization during plasticity of...

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Vydáno v:J Neurosci
Hlavní autoři: Pennacchietti, Francesca, Vascon, Sebastiano, Nieus, Thierry, Rosillo, Christian, Das, Sabyasachi, Tyagarajan, Shiva K., Diaspro, Alberto, Del Bue, Alessio, Petrini, Enrica Maria, Barberis, Andrea, Cella Zanacchi, Francesca
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2017
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6589977/
https://ncbi.nlm.nih.gov/pubmed/28073939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0514-16.2016
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