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IL-1 in osteoarthritis: time for a critical review of the literature
The concept of interleukin-1 (IL-1) as a target in osteoarthritis (OA) has been an attractive one for many years. It is a highly potent inducer of cartilage degradation, causing the induction of mRNA and controlling the bioavailability of disease-relevant proteases such as ADAMTS5 and MMP13. It driv...
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| Publicado en: | F1000Res |
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| Autor Principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
F1000 Research Limited
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6589928/ https://ncbi.nlm.nih.gov/pubmed/31249675 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.18831.1 |
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