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3D Cell-Based Assays for Drug Screens: Challenges in Imaging, Image Analysis, and High-Content Analysis

The introduction of more relevant cell models in early preclinical drug discovery, combined with high-content imaging and automated analysis, is expected to increase the quality of compounds progressing to preclinical stages in the drug development pipeline. In this review we discuss the current swi...

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Bibliographic Details
Published in:SLAS Discov
Main Authors: Booij, Tijmen H., Price, Leo S., Danen, Erik H. J.
Format: Artigo
Language:Inglês
Published: SAGE Publications 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6589915/
https://ncbi.nlm.nih.gov/pubmed/30817892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2472555219830087
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