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Interactions of the dynein-2 intermediate chain WDR34 with the light chains are required for ciliary retrograde protein trafficking

The dynein-2 complex drives retrograde ciliary protein trafficking by associating with the intraflagellar transport (IFT) machinery, containing IFT-A and IFT-B complexes. We recently showed that the dynein-2 complex, which comprises 11 subunits, can be divided into three subcomplexes: DYNC2H1–DYNC2L...

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Détails bibliographiques
Publié dans:Mol Biol Cell
Auteurs principaux: Tsurumi, Yuta, Hamada, Yuki, Katoh, Yohei, Nakayama, Kazuhisa
Format: Artigo
Langue:Inglês
Publié: The American Society for Cell Biology 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6589695/
https://ncbi.nlm.nih.gov/pubmed/30649997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E18-10-0678
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