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Cellular senescence in the lung across the age spectrum

Cellular senescence results in cell cycle arrest with secretion of cytokines, chemokines, growth factors, and remodeling proteins (senescence-associated secretory phenotype; SASP) that have autocrine and paracrine effects on the tissue microenvironment. SASP can promote remodeling, inflammation, inf...

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Detalles Bibliográficos
Publicado en:Am J Physiol Lung Cell Mol Physiol
Autores principales: Parikh, Pavan, Wicher, Sarah, Khandalavala, Karl, Pabelick, Christina M., Britt, Rodney D., Prakash, Y. S.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6589594/
https://ncbi.nlm.nih.gov/pubmed/30785345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00424.2018
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