G-protein–coupled formyl peptide receptors play a dual role in neutrophil chemotaxis and bacterial phagocytosis

A dogma of innate immunity is that neutrophils use G-protein–coupled receptors (GPCRs) for chemoattractant to chase bacteria through chemotaxis and then use phagocytic receptors coupled with tyrosine kinases to destroy opsonized bacteria via phagocytosis. Our current work showed that G-protein–coupl...

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Udgivet i:Mol Biol Cell
Main Authors: Wen, Xi, Xu, Xuehua, Sun, Wenxiang, Chen, Keqiang, Pan, Miao, Wang, Ji Ming, Bolland, Silvia M., Jin, Tian
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2019
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6589574/
https://ncbi.nlm.nih.gov/pubmed/30540534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E18-06-0358
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