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Inter-helical conformational preferences of HIV-1 TAR-RNA from maximum occurrence analysis of NMR data and molecular dynamics simulations

Detecting conformational heterogeneity in biological macromolecules is a key for the understanding of their biological function. We here provide a comparison between two independent approaches to assess conformational heterogeneity: molecular dynamics simulations, performed without inclusion of any...

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Publicado en:Phys Chem Chem Phys
Autores principales: Andrałojć, Witold, Ravera, Enrico, Salmon, Loïc, Parigi, Giacomo, Al-Hashimi, Hashim M., Luchinat, Claudio
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6589165/
https://ncbi.nlm.nih.gov/pubmed/26360616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5cp03993b
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