Observed Changes in Natural Killer and T cell Phenotypes with Evaluation of Immune Outcome in a Longitudinal Cohort Following Sofosbuvir-Based Therapy for Chronic Hepatitis C Infection

BACKGROUND: Chronic hepatitis C virus (HCV) infection diminishes immune function through cell exhaustion and repertoire alteration. Direct acting antiviral (DAA)-based therapy can restore immune cell subset function and reduce exhaustion states. However, the extent of immune modulation following DAA...

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Detalhes bibliográficos
Publicado no:Open Forum Infect Dis
Main Authors: Stevenson, Timothy J, Barbour, Youssef, McMahon, Brian J, Townshend-Bulson, Lisa, Hewitt, Annette M, Espera, Hannah G F, Homan, Chriss, Holck, Peter, Luna, Sarah V, Knall, Cindy, Simons, Brenna C
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Major Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6589029/
https://ncbi.nlm.nih.gov/pubmed/31249845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofz223
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