Longitudinal immunosequencing in healthy people reveals persistent T cell receptors rich in highly public receptors

BACKGROUND: The adaptive immune system maintains a diversity of T cells capable of recognizing a broad array of antigens. Each T cell’s specificity for antigens is determined by its T cell receptors (TCRs), which together across all T cells form a repertoire of millions of unique receptors in each i...

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Detalhes bibliográficos
Publicado no:BMC Immunol
Main Authors: Chu, Nathaniel D., Bi, Haixin Sarah, Emerson, Ryan O., Sherwood, Anna M., Birnbaum, Michael E., Robins, Harlan S., Alm, Eric J.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6588944/
https://ncbi.nlm.nih.gov/pubmed/31226930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12865-019-0300-5
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