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Treatment with metformin in twelve patients with Lafora disease
BACKGROUND: Lafora disease (LD) is a rare, lethal, progressive myoclonus epilepsy for which no targeted therapy is currently available. Studies on a mouse model of LD showed a good response to metformin, a drug with a well known neuroprotective effect. For this reason, in 2016, the European Medicine...
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| 出版年: | Orphanet J Rare Dis |
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| 主要な著者: | , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6588886/ https://ncbi.nlm.nih.gov/pubmed/31227012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13023-019-1132-3 |
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