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Development of glial restricted human neural stem cells for oligodendrocyte differentiation in vitro and in vivo
In this study, we have developed highly expandable neural stem cells (NSCs) from HESCs and iPSCs that artificially express the oligodendrocyte (OL) specific transcription factor gene Zfp488. This is enough to restrict them to an exclusive oligodendrocyte progenitor cell (OPC) fate during differentia...
में बचाया:
| में प्रकाशित: | Sci Rep |
|---|---|
| मुख्य लेखकों: | , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Nature Publishing Group UK
2019
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6588721/ https://ncbi.nlm.nih.gov/pubmed/31227736 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45247-3 |
| टैग : |
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