Apoptosis of cancer cells is triggered by selective crosslinking and inhibition of receptor tyrosine kinases

Receptor tyrosine kinases (RTK) have been the most prevalent therapeutic targets in anti-cancer drug development. However, the emergence of drug resistance toward single target RTK inhibitors remains a major challenge to achieve long-term remissions. Development of alternative RTK inhibitory strateg...

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Vydáno v:Commun Biol
Hlavní autoři: Wang, Kaidi, Wang, Xuan, Hou, Yiying, Zhou, Huihui, Mai, Kangsen, He, Gen
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6588694/
https://ncbi.nlm.nih.gov/pubmed/31263775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0484-5
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