Immunization with merozoite surface protein 2 fused to a Plasmodium-specific carrier protein elicits strain-specific and strain-transcending, opsonizing antibody

Vaccine trials and cohort studies in Plasmodium falciparum endemic areas indicate that naturally-acquired and vaccine-induced antibodies to merozoite surface protein 2 (MSP2) are associated with resistance to malaria. These data indicate that PfMSP2 has significant potential as a component of a mult...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Eacret, Jacqueline S., Gonzales, Donna M., Franks, Raymond G., Burns, James M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6588637/
https://ncbi.nlm.nih.gov/pubmed/31227760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45440-4
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