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An in vitro pressure model towards studying the response of primary retinal ganglion cells to elevated hydrostatic pressures

Glaucoma is a leading cause of blindness characterized by progressive degeneration of retinal ganglion cells (RGCs). A well-established risk factor for the development and progression of glaucoma is elevation of intraocular pressure (IOP). However, how elevated IOP leads to RGC degeneration remains...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wu, Jing, Mak, Heather Kayew, Chan, Yau Kei, Lin, Chen, Kong, Cihang, Leung, Christopher Kai Shun, Shum, Ho Cheung
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6588599/
https://ncbi.nlm.nih.gov/pubmed/31227762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45510-7
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