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Minimal exposure of lipid II cycle intermediates triggers cell wall antibiotic resistance
Cell wall antibiotics are crucial for combatting the emerging wave of resistant bacteria. Yet, our understanding of antibiotic action is limited, as many strains devoid of all resistance determinants display far higher antibiotic tolerance in vivo than suggested by the antibiotic-target binding affi...
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| Veröffentlicht in: | Nat Commun |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6588590/ https://ncbi.nlm.nih.gov/pubmed/31227716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10673-4 |
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