Conformational proofreading of distant 40S ribosomal subunit maturation events by a long-range communication mechanism

Eukaryotic ribosomes are synthesized in a hierarchical process driven by a plethora of assembly factors, but how maturation events at physically distant sites on pre-ribosomes are coordinated is poorly understood. Using functional analyses and cryo-EM, we show that ribosomal protein Rps20 orchestrat...

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Gepubliceerd in:Nat Commun
Hoofdauteurs: Mitterer, Valentin, Shayan, Ramtin, Ferreira-Cerca, Sébastien, Murat, Guillaume, Enne, Tanja, Rinaldi, Dana, Weigl, Sarah, Omanic, Hajrija, Gleizes, Pierre-Emmanuel, Kressler, Dieter, Plisson-Chastang, Celia, Pertschy, Brigitte
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6588571/
https://ncbi.nlm.nih.gov/pubmed/31227701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10678-z
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