Reduced SNAP25 protein fragmentation contributes to SNARE complex dysregulation in schizophrenia postmortem brain

Recent studies associated schizophrenia with enhanced functionality of the presynaptic SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) complex. Altered degradation pathways of the three core SNARE proteins: synaptosomal-associated protein 25 (SNAP25), syntaxin-1 and ves...

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Publicado en:Neuroscience
Main Authors: Ramos-Miguel, Alfredo, Gicas, Kristina, Alamri, Jehan, Beasley, Clare L., Dwork, Andrew J., Mann, J. John, Rosoklija, Gorazd, Cai, Fang, Song, Weihong, Barr, Alasdair M., Honer, William G.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6588506/
https://ncbi.nlm.nih.gov/pubmed/30579835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2018.12.015
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