Doxycycline Reduces Scar Thickness and Improves Collagen Architecture

OBJECTIVE: To investigate the effects of local doxycycline administration on skin scarring. BACKGROUND: Skin scarring represents a major source of morbidity for surgical patients. Doxycycline, a tetracycline antibiotic with off-target effects on the extracellular matrix, has demonstrated antifibroti...

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Detalhes bibliográficos
Publicado no:Ann Surg
Main Authors: Moore, Alessandra L., desJardins-Park, Heather E., Duoto, Bryan A., Mascharak, Shamik, Murphy, Matthew P., Irizarry, Dre M., Foster, Deshka S., Jones, Ruth E., Barnes, Leandra A., Marshall, Clement D., Ransom, Ryan C., Wernig, Gerlinde, Longaker, Michael T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6588503/
https://ncbi.nlm.nih.gov/pubmed/30585822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SLA.0000000000003172
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