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Fragile X Mental Retardation Protein Positively Regulates PKA Anchor Rugose and PKA Activity to Control Actin Assembly in Learning/Memory Circuitry

Recent work shows Fragile X Mental Retardation Protein (FMRP) drives the translation of very large proteins (>2000 aa) mediating neurodevelopment. Loss of function results in Fragile X syndrome (FXS), the leading heritable cause of intellectual disability (ID) and autism spectrum disorder (ASD)....

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Bibliografische gegevens
Gepubliceerd in:Neurobiol Dis
Hoofdauteurs: Sears, James C., Choi, Woong Jae, Broadie, Kendal
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6588493/
https://ncbi.nlm.nih.gov/pubmed/30771457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2019.02.004
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