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Fragile X Mental Retardation Protein Positively Regulates PKA Anchor Rugose and PKA Activity to Control Actin Assembly in Learning/Memory Circuitry
Recent work shows Fragile X Mental Retardation Protein (FMRP) drives the translation of very large proteins (>2000 aa) mediating neurodevelopment. Loss of function results in Fragile X syndrome (FXS), the leading heritable cause of intellectual disability (ID) and autism spectrum disorder (ASD)....
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| Published in: | Neurobiol Dis |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6588493/ https://ncbi.nlm.nih.gov/pubmed/30771457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2019.02.004 |
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