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Deferoxamine therapy reduces brain hemin accumulation after intracerebral hemorrhage in piglets

Hemopexin (Hpx) is critical for hemin scavenging after the erythrocyte lysis that occurs following intracerebral hemorrhage (ICH). Low-density lipoprotein receptor-related protein-1 (LRP1, also called CD91) is an important receptor through which the hemin-Hpx complex can undergo endocytosis. This st...

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Publicat a:Exp Neurol
Autors principals: Hu, Shengli, Hua, Ya, Keep, Richard F., Feng, Hua, Xi, Guohua
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6588480/
https://ncbi.nlm.nih.gov/pubmed/31078524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2019.05.003
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