High Intrarenal Lactate Production Inhibits the Renal Pseudohypoxic Response to Acutely Induced Hypoxia in Diabetes

Intrarenal hypoxia develops within a few days after the onset of insulinopenic diabetes in an experimental animal model (ie, a model of type-1 diabetes). Although diabetes-induced hypoxia results in increased renal lactate formation, mitochondrial function is well maintained, a condition commonly re...

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Detalhes bibliográficos
Publicado no:Tomography
Main Authors: Laustsen, Christoffer, Lipsø, Kasper, Østergaard, Jakob Appel, Nielsen, Per Mose, Bertelsen, Lotte Bonde, Flyvbjerg, Allan, Pedersen, Michael, Palm, Fredrik, Ardenkjær-Larsen, Jan Henrik
Formato: Artigo
Idioma:Inglês
Publicado em: Grapho Publications, LLC 2019
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Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6588198/
https://ncbi.nlm.nih.gov/pubmed/31245545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18383/j.tom.2019.00003
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