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Reactive astrocytes in multiple sclerosis impair neuronal outgrowth through TRPM7‐mediated chondroitin sulfate proteoglycan production

Multiple sclerosis (MS) is a chronic inflammatory disorder of the central nervous system (CNS), characterized by inflammation‐mediated demyelination, axonal injury and neurodegeneration. The mechanisms underlying impaired neuronal function are not fully understood, but evidence is accumulating that...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Glia
Hauptverfasser: Kamermans, Alwin, Planting, Kirsten E., Jalink, Kees, van Horssen, Jack, de Vries, Helga E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley & Sons, Inc. 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6587975/
https://ncbi.nlm.nih.gov/pubmed/30453391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.23526
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