Bile Microinfarcts in Cholestasis Are Initiated by Rupture of the Apical Hepatocyte Membrane and Cause Shunting of Bile to Sinusoidal Blood

Bile duct ligation (BDL) is an experimental procedure that mimics obstructive cholestatic disease. One of the early consequences of BDL in rodents is the appearance of so‐called bile infarcts that correspond to Charcot‐Gombault necrosis in human cholestasis. The mechanisms causing bile infarcts and...

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Detalhes bibliográficos
Publicado no:Hepatology
Main Authors: Ghallab, Ahmed, Hofmann, Ute, Sezgin, Selahaddin, Vartak, Nachiket, Hassan, Reham, Zaza, Ayham, Godoy, Patricio, Schneider, Kai Markus, Guenther, Georgia, Ahmed, Yasser A., Abbas, Aya A., Keitel, Verena, Kuepfer, Lars, Dooley, Steven, Lammert, Frank, Trautwein, Christian, Spiteller, Michael, Drasdo, Dirk, Hofmann, Alan F., Jansen, Peter L.M., Hengstler, Jan G., Reif, Raymond
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6587841/
https://ncbi.nlm.nih.gov/pubmed/30102412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.30213
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