Fetal fraction‐based risk algorithm for non‐invasive prenatal testing: screening for trisomies 13 and 18 and triploidy in women with low cell‐free fetal DNA

OBJECTIVE: To identify pregnancies at increased risk for trisomy 13, trisomy 18 or triploidy attributable to low fetal fraction (FF). METHODS: A FF‐based risk (FFBR) model was built using data from more than 165 000 singleton pregnancies referred for single‐nucleotide polymorphism (SNP)‐based non‐in...

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Publicat a:Ultrasound Obstet Gynecol
Autors principals: McKanna, T., Ryan, A., Krinshpun, S., Kareht, S., Marchand, K., Grabarits, C., Ali, M., McElheny, A., Gardiner, K., LeChien, K., Hsu, M., Saltzman, D., Stosic, M., Martin, K., Benn, P.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley & Sons, Ltd. 2018
Matèries:
Original Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6587793/
https://ncbi.nlm.nih.gov/pubmed/30014528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/uog.19176
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