Lysyl oxidase‐like 2 is a regulator of angiogenesis through modulation of endothelial‐to‐mesenchymal transition

Lysyl oxidase‐like 2 (LOXL2) belongs to the family of lysyl oxidases, and as such promotes crosslinking of collagens and elastin by oxidative deamination of lysine residues. In endothelial cells (ECs), LOXL2 is involved in crosslinking and scaffolding of collagen IV. Additionally, several reports ha...

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Bibliographic Details
Published in:J Cell Physiol
Main Authors: de Jong, Olivier G., van der Waals, Lizet M., Kools, Farah R. W., Verhaar, Marianne C., van Balkom, Bas W. M.
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2018
Subjects:
Original Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6587725/
https://ncbi.nlm.nih.gov/pubmed/30387148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.27695
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