Comparison of the metabolism of 10 chemicals in human and pig skin explants

Skin metabolism is important to consider when assessing local toxicity and/or penetration of chemicals and their metabolites. If human skin supply is limited, pig skin can be used as an alternative. To identify any species differences, we have investigated the metabolism of 10 chemicals in a pig and...

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Vydáno v:J Appl Toxicol
Hlavní autoři: Géniès, C., Jamin, E. L., Debrauwer, L., Zalko, D., Person, E. N., Eilstein, J., Grégoire, S., Schepky, A., Lange, D., Ellison, C., Roe, A., Salhi, S., Cubberley, R., Hewitt, N. J., Rothe, H., Klaric, M., Duplan, H., Jacques‐Jamin, C.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6587507/
https://ncbi.nlm.nih.gov/pubmed/30345528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jat.3730
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