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The pearl necklace model in protein A chromatography: Molecular mechanisms at the resin interface

Staphylococcal protein A chromatography is an established core technology for monoclonal antibody purification and capture in the downstream processing. MabSelect SuRe involves a tetrameric chain of a recombinant form of the B domain of staphylococcal protein A, called the Z‐domain. Little is known...

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Bibliographic Details
Published in:Biotechnol Bioeng
Main Authors: L. Silva, Goncalo, Plewka, Jacek, Lichtenegger, Helga, Dias‐Cabral, Ana C., Jungbauer, Alois, Tscheließnig, Rupert
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6587469/
https://ncbi.nlm.nih.gov/pubmed/30252938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.26843
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