High predictive efficacy of integrase strand transfer inhibitors in perinatally HIV-1-infected African children in therapeutic failure of first- and second-line antiretroviral drug regimens recommended by the WHO

OBJECTIVES: The predictive efficacy of integrase (IN) strand transfer inhibitors (INSTIs) was investigated in HIV-infected children born to HIV-infected mothers in Africa. METHODS: Plasma was collected at the Complexe Pédiatrique of Bangui, Central African Republic, from INSTI-naive children (n = 8)...

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Detalhes bibliográficos
Publicado no:J Antimicrob Chemother
Main Authors: Mboumba Bouassa, Ralph-Sydney, Mossoro-Kpinde, Christian Diamant, Gody, Jean-Chrysostome, Veyer, David, Péré, Hélène, Matta, Mathieu, Robin, Leman, Grésenguet, Gérard, Charpentier, Charlotte, Bélec, Laurent
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6587428/
https://ncbi.nlm.nih.gov/pubmed/30891603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkz099
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