The m6A demethylase ALKBH5 controls trophoblast invasion at the maternal-fetal interface by regulating the stability of CYR61 mRNA

N(6)-Methyladenosine (m(6)A) is the most prevalent internal modification in mammalian mRNAs. Although m(6)A is important in many biological processes, its roles in the placenta are unclear. Methods: Levels of global mRNA m(6)A methylation and ALKBH5 expression in recurrent miscarriage (RM) patients...

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Podrobná bibliografie
Vydáno v:Theranostics
Hlavní autoři: Li, Xiao-Cui, Jin, Feng, Wang, Bei-Ying, Yin, Xiang-Jie, Hong, Wei, Tian, Fu-Ju
Médium: Artigo
Jazyk:Inglês
Vydáno: Ivyspring International Publisher 2019
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6587351/
https://ncbi.nlm.nih.gov/pubmed/31281518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.31868
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