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Immobilization Decreases FOXO3a Phosphorylation and Increases Autophagy-Related Gene and Protein Expression in Human Skeletal Muscle

Immobilization of the lower limbs promotes a catabolic state that reduces muscle mass, whereas physical training promotes an anabolic state that increases muscle mass. Understanding the molecular mechanisms underlying this is of clinical interest, as loss of muscle mass is a major complication to cr...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Møller, Andreas Buch, Vendelbo, Mikkel Holm, Schjerling, Peter, Couppé, Christian, Møller, Niels, Kjær, Michael, Hansen, Mette, Jessen, Niels
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6587099/
https://ncbi.nlm.nih.gov/pubmed/31258486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.00736
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