Ursolic Acid Reverses the Chemoresistance of Breast Cancer Cells to Paclitaxel by Targeting MiRNA-149-5p/MyD88

Paclitaxel (PTX) is widely used as a front-line chemotherapy for breast cancer treatment. However, its clinical applications are limited by the development of chemoresistance. The objective of this study was to investigate the reversal effects of ursolic acid (UA) on PTX resistance and the possible...

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Veröffentlicht in:Front Oncol
Hauptverfasser: Xiang, Fenfen, Fan, Yan, Ni, Zhenhua, Liu, Qiaoli, Zhu, Zhaowei, Chen, Zixi, Hao, Wenbin, Yue, Honghong, Wu, Rong, Kang, Xiangdong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Oncology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6587017/
https://ncbi.nlm.nih.gov/pubmed/31259152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00501
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