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Computational analysis of single-cell transcriptomics data elucidates the stabilization of Oct4 expression in the E3.25 mouse preimplantation embryo

Our computational analysis focuses on the 32- to 64-cell mouse embryo transition, Embryonic day (E3.25), whose study in literature is concentrated mainly on the search for an early onset of the second cell-fate decision, the specification of the inner cell mass (ICM) to primitive endoderm (PE) and e...

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Pubblicato in:Sci Rep
Autori principali: Gerovska, Daniela, Araúzo-Bravo, Marcos J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6586892/
https://ncbi.nlm.nih.gov/pubmed/31222057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-45438-y
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