MCRIP1 promotes the expression of lung-surfactant proteins in mice by disrupting CtBP-mediated epigenetic gene silencing

Proper regulation of epigenetic states of chromatin is crucial to achieve tissue-specific gene expression during embryogenesis. The lung-specific gene products, surfactant proteins B (SP-B) and C (SP-C), are synthesized in alveolar epithelial cells and prevent alveolar collapse. Epigenetic regulatio...

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Pubblicato in:Commun Biol
Autori principali: Weng, Jane S., Nakamura, Takanori, Moriizumi, Hisashi, Takano, Hiroshi, Yao, Ryoji, Takekawa, Mutsuhiro
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6586819/
https://ncbi.nlm.nih.gov/pubmed/31240265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0478-3
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