Mesenchymal Stem Cell Therapy for Doxorubicin-Induced Cardiomyopathy: Potential Mechanisms, Governing Factors, and Implications of the Heart Stem Cell Debate

Over the past decades, researchers have reported several mechanisms for doxorubicin (DOX)-induced cardiomyopathy, including oxidative stress, inflammation, and apoptosis. Another mechanism that has been suggested is that DOX interferes with the cell cycle and induces oxidative stress in C-kit+ cells...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Abushouk, Abdelrahman Ibrahim, Salem, Amr Muhammad Abdo, Saad, Anas, Afifi, Ahmed M., Afify, Abdelrahman Yousry, Afify, Hesham, Salem, Hazem S.E., Ghanem, Esraa, Abdel-Daim, Mohamed M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6586740/
https://ncbi.nlm.nih.gov/pubmed/31258475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00635
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