The Group B Streptococcal surface antigen I/II protein, BspC, interacts with host vimentin to promote adherence to brain endothelium and inflammation during the pathogenesis of meningitis

Streptococcus agalactiae (Group B Streptococcus, GBS) normally colonizes healthy adults but can cause invasive disease, such as meningitis, in the newborn. To gain access to the central nervous system, GBS must interact with and penetrate brain or meningeal blood vessels; however, the exact mechanis...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Deng, Liwen, Spencer, Brady L., Holmes, Joshua A., Mu, Rong, Rego, Sara, Weston, Thomas A., Hu, Yoonsung, Sanches, Glenda F., Yoon, Sunghyun, Park, Nogi, Nagao, Prescilla E., Jenkinson, Howard F., Thornton, Justin A., Seo, Keun Seok, Nobbs, Angela H., Doran, Kelly S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6586375/
https://ncbi.nlm.nih.gov/pubmed/31181121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007848
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