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Predicting three-dimensional genome organization with chromatin states
We introduce a computational model to simulate chromatin structure and dynamics. Starting from one-dimensional genomics and epigenomics data that are available for hundreds of cell types, this model enables de novo prediction of chromatin structures at five-kilo-base resolution. Simulated chromatin...
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| Udgivet i: | PLoS Comput Biol |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6586364/ https://ncbi.nlm.nih.gov/pubmed/31181064 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007024 |
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