Intravenous delivery of granulocyte-macrophage colony stimulating factor impairs survival in lipopolysaccharide-induced sepsis

BACKGROUND: Cell-based therapies with bone marrow-derived progenitor cells (BMDPC) lead to an improved clinical outcome in animal sepsis models. In the present study we evaluated the ability of granulocyte macrophage-colony stimulating factor (GM-CSF) to mobilize BMDPC in a lipopolysaccharide (LPS)-...

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Pubblicato in:PLoS One
Autori principali: Krebs, Jörg, Hillenbrand, Alexander, Tsagogiorgas, Charalambos, Patry, Christian, Tönshoff, Burkhard, Yard, Benito, Beck, Grietje, Rafat, Neysan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6586330/
https://ncbi.nlm.nih.gov/pubmed/31220157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0218602
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