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Isolation of thermally sensitive protein-binding oligonucleotides on a microchip
This paper presents a microfluidic chip capable of isolating thermally sensitive protein-binding aptamer candidates. The chip makes use of bead-immobilized target molecules and DNA (deoxyribonucleic acid) sequences to enable a simplified chip design, in which affinity selection and PCR (polymerase c...
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| Publié dans: | Microfluid Nanofluidics |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6586242/ https://ncbi.nlm.nih.gov/pubmed/31223297 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10404-015-1604-2 |
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