A longitudinal multimodal in vivo molecular imaging study of the 3xTg-AD mouse model shows progressive early hippocampal and taurine loss

The understanding of the natural history of Alzheimer’s disease (AD) and temporal trajectories of in vivo molecular mechanisms requires longitudinal approaches. A behavioral and multimodal imaging study was performed at 4/8/12 and 16 months of age in a triple transgenic mouse model of AD (3xTg-AD)....

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Publicat a:Hum Mol Genet
Autors principals: Chiquita, Samuel, Ribeiro, Mário, Castelhano, João, Oliveira, Francisco, Sereno, José, Batista, Marta, Abrunhosa, Antero, Rodrigues-Neves, Ana C, Carecho, Rafael, Baptista, Filipa, Gomes, Catarina, Moreira, Paula I, Ambrósio, António F, Castelo-Branco, Miguel
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
Matèries:
General Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6586150/
https://ncbi.nlm.nih.gov/pubmed/30816415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddz045
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