Elevated serum Activin A in chronic obstructive pulmonary disease with skeletal muscle wasting

OBJECTIVE: Muscle wasting contributes to the reduced quality of life and increased mortality in chronic obstructive pulmonary disease (COPD). Muscle atrophy in mice with cachexia was caused by Activin A binding to ActRIIB. The role of circulating Activin A leading to muscle atrophy in COPD remains e...

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Veröffentlicht in:Clinics (Sao Paulo)
Hauptverfasser: Zhou, Guanghui, Gui, Xianhua, Chen, Ruhua, Fu, Xingli, Ji, Xiuhai, Ding, Hui
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2019
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6585865/
https://ncbi.nlm.nih.gov/pubmed/31271588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6061/clinics/2019/e981
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