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Lentivirus‐mediated disintegrin and metalloproteinase 17 RNA interference reversed the acquired resistance to gefitinib in lung adenocarcinoma cells in vitro

Objective: The aim of the study is to evaluate the effects of silencing a disintegrin and metalloproteinase 17 (ADAM17) gene expression by lentivirus‐mediated RNA interference (RNAi) in the gefitinib‐resistant lung adenocarcinoma cells, and then to explore whether the recombinant lentivirus mediated...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biotechnol Prog
Hauptverfasser: Li, Ya‐Qing, Liu, Yuan‐Shun, Ying, Xi‐Wang, Zhou, Hong‐Bin, Wang, Zhehua, Wu, Sheng‐Chang, Yan, Jian‐Ping, Jing, Yu‐Ting, Yang, Yang
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6585635/
https://ncbi.nlm.nih.gov/pubmed/28960861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/btpr.2564
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