Senescent Kidney Cells in Hypertensive Patients Release Urinary Extracellular Vesicles

BACKGROUND: Hypertension may be associated with renal cellular injury. Cells in distress release extracellular vesicles (EVs), and their numbers in urine may reflect renal injury. Cellular senescence, an irreversible growth arrest in response to a noxious milieu, is characterized by release of proin...

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Bibliografiske detaljer
Udgivet i:J Am Heart Assoc
Main Authors: Santelli, Adrian, Sun, In O., Eirin, Alfonso, Abumoawad, Abdelrhman M., Woollard, John R., Lerman, Amir, Textor, Stephen C., Puranik, Amrutesh S., Lerman, Lilach O.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6585370/
https://ncbi.nlm.nih.gov/pubmed/31433703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.119.012584
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