Senescent Kidney Cells in Hypertensive Patients Release Urinary Extracellular Vesicles

BACKGROUND: Hypertension may be associated with renal cellular injury. Cells in distress release extracellular vesicles (EVs), and their numbers in urine may reflect renal injury. Cellular senescence, an irreversible growth arrest in response to a noxious milieu, is characterized by release of proin...

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Bibliographische Detailangaben
Veröffentlicht in:J Am Heart Assoc
Hauptverfasser: Santelli, Adrian, Sun, In O., Eirin, Alfonso, Abumoawad, Abdelrhman M., Woollard, John R., Lerman, Amir, Textor, Stephen C., Puranik, Amrutesh S., Lerman, Lilach O.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6585370/
https://ncbi.nlm.nih.gov/pubmed/31433703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.119.012584
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