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Suppressive Effects of Cooling Compounds Icilin on Penicillin G-Induced Epileptiform Discharges in Anesthetized Rats

More than 30% of patients with epilepsy are refractory and have inadequate seizure control. Focal cortical cooling (FCC) suppresses epileptiform discharges (EDs) in patients with refractory focal cortical epilepsy. However, little is known about the mechanism by which FCC inhibits seizures at 15°C,...

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Publicado en:Front Pharmacol
Autores principales: Moriyama, Hiroshi, Nomura, Sadahiro, Kida, Hiroyuki, Inoue, Takao, Imoto, Hirochika, Maruta, Yuichi, Fujiyama, Yuichi, Mitsushima, Dai, Suzuki, Michiyasu
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6585232/
https://ncbi.nlm.nih.gov/pubmed/31263415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00652
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