Frequentist p-values for large-scale-single step genome-wide association, with an application to birth weight in American Angus cattle

BACKGROUND: Single-step genomic best linear unbiased prediction (SSGBLUP) is a comprehensive method for genomic prediction. Point estimates of marker effects from SSGBLUP are often used for genome-wide association studies (GWAS) without a formal framework of hypothesis testing. Our objective was to...

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Dettagli Bibliografici
Pubblicato in:Genet Sel Evol
Autori principali: Aguilar, Ignacio, Legarra, Andres, Cardoso, Fernando, Masuda, Yutaka, Lourenco, Daniela, Misztal, Ignacy
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
Soggetti:
Short Communication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6584984/
https://ncbi.nlm.nih.gov/pubmed/31221101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12711-019-0469-3
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