Sigma-1 Receptor Inhibition Reduces Neuropathic Pain Induced by Partial Sciatic Nerve Transection in Mice by Opioid-Dependent and -Independent Mechanisms

Sigma-1 (σ(1)) receptor antagonists are promising tools for neuropathic pain treatment, but it is unknown whether σ(1) receptor inhibition ameliorates the neuropathic signs induced by nerve transection, in which the pathophysiological mechanisms and response to drug treatment differ from other neuro...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Bravo-Caparrós, Inmaculada, Perazzoli, Gloria, Yeste, Sandra, Cikes, Domagoj, Baeyens, José Manuel, Cobos, Enrique José, Nieto, Francisco Rafael
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6584826/
https://ncbi.nlm.nih.gov/pubmed/31263413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00613
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados