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Glucocorticoid receptor-dependent induction of cripto-1 (one-eyed pinhead) inhibits zebrafish caudal fin regeneration

We previously used a chemical genetics approach with the larval zebrafish to identify small molecule inhibitors of tissue regeneration. This led to the discovery that glucocorticoids (GC) block early stages of tissue regeneration by the inappropriate activation of the glucocorticoid receptor (GR). W...

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Detalhes bibliográficos
Publicado no:Toxicol Rep
Main Authors: Garland, Michael A., Sengupta, Sumitra, Mathew, Lijoy K., Truong, Lisa, de Jong, Esther, Piersma, Aldert H., La Du, Jane, Tanguay, Robert L.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6584771/
https://ncbi.nlm.nih.gov/pubmed/31249786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxrep.2019.05.013
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