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Glucocorticoid receptor-dependent induction of cripto-1 (one-eyed pinhead) inhibits zebrafish caudal fin regeneration

We previously used a chemical genetics approach with the larval zebrafish to identify small molecule inhibitors of tissue regeneration. This led to the discovery that glucocorticoids (GC) block early stages of tissue regeneration by the inappropriate activation of the glucocorticoid receptor (GR). W...

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Détails bibliographiques
Publié dans:Toxicol Rep
Auteurs principaux: Garland, Michael A., Sengupta, Sumitra, Mathew, Lijoy K., Truong, Lisa, de Jong, Esther, Piersma, Aldert H., La Du, Jane, Tanguay, Robert L.
Format: Artigo
Langue:Inglês
Publié: Elsevier 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6584771/
https://ncbi.nlm.nih.gov/pubmed/31249786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxrep.2019.05.013
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