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Recursive model for dose-time responses in pharmacological studies

BACKGROUND: Clinical studies often track dose-response curves of subjects over time. One can easily model the dose-response curve at each time point with Hill equation, but such a model fails to capture the temporal evolution of the curves. On the other hand, one can use Gompertz equation to model t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:BMC Bioinformatics
Hauptverfasser: Dhruba, Saugato Rahman, Rahman, Aminur, Rahman, Raziur, Ghosh, Souparno, Pal, Ranadip
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6584530/
https://ncbi.nlm.nih.gov/pubmed/31216980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-019-2831-4
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