Enhanced ROBO4 is mediated by up‐regulation of HIF‐1α/SP1 or reduction in miR‐125b‐5p/miR‐146a‐5p in diabetic retinopathy

Retinal cell damage caused by diabetes leads to retinal microvascular injury. Roundabout 4 (ROBO4) is involved in angiogenesis, which varies with the development of diabetic retinopathy (DR). Here, we explored the transcriptional regulation and microRNA‐mediated modulation of ROBO4 expression and re...

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Foilsithe in:J Cell Mol Med
Main Authors: Gong, Qiaoyun, Xie, Jia'nan, Li, Ying, Liu, Yang, Su, Guanfang
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2019
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Original Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6584523/
https://ncbi.nlm.nih.gov/pubmed/31094072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14369
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